Study of Atenolol Influence on Blood Pressure During Resistance Exercise

University of Sao Paulo10 enrolled

Overview

The study was designed to investigate if atenolol is able to blunt blood pressure increase during resistance exercise in hypertensive subjects.

The study compared intra-arterial blood pressure responses during leg-extension resistance exercise performed to fatigue at 40, 80 and 100% of 1 RM in hypertensive patients receiving placebo (first) and atenolol (second) on a single blind manner.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

SINGLE

Enrollment

Conditions

Blood Pressure Exercise

Interventions

atenololDRUG

25 mg/day, twice a day for 6 weeks

Eligibility

Sex: ALLMin age: 30 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * hypertension with blood pressure levels below 160/105 mmHg under placebo. * age between 30 and 60 years * nonobese Exclusion Criteria: * target organ lesion * cardiovascular risk factor * cardiovascular disease * physically active

Locations (1)

University of São Paulo

São Paulo, São Paulo, Brazil

Outcomes

Primary Outcomes

blood pressure during resistance exercise

Time frame: 6 weeks

Data from ClinicalTrials.gov

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