Study of Stereotactic Body Radiation Therapy Using Tomotherapy for Metastatic Tumors to the Liver

Inclusion Criteria: * Histologic confirmation of solid primary tumor metastatic to liver * Age greater than or equal to 18 years old * Zubrod performance status less than or equal to 1 * Negative pregnancy test for women of child bearing potential * Informed consent * Less than or equal to 3 liver metastases * Each lesion must be less than or equal to 6 cm in maximal diameter * No prior radiation to lesions being treated * Patient is not a surgical candidate or refuses surgery * Absolute neutrophil count ≥ 1800 * Platelets ≥ 100000 * Hemoglobin ≥8.0 * Systemic therapy (chemotherapy) completed at least 2 weeks prior to SBRT * At time of radiation treatment planning, at least 700 cc of normal liver must receive less than 15 Gy Exclusion Criteria: * Contraindications to radiation * Pregnant or lactating females who chose to breast feed * Patients must have recovered from toxicity of prior therapy * Any co morbid condition that' in the view of the attending physician' renders the patient at high risk from treatment complications * Patients currently receiving anticoagulation with coumadin or IV heparin * Liver cirrhosis * Clinical ascites * Bilirubin \> 3, Albumin \< 2.5, liver enzymes 3 times above normal, Creatinine \> 1.8