This is a phase 2 study of the HSP90 inhibitor, STA-9090 (ganetespib) in subjects with stage IIIB or IV non-small cell lung cancer (NSCLC).
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
113
STA-9090 IV infusion once per week for three consecutive weeks followed by a 1 week dose-free interval
Arizona Cancer Center; University of Arizona
Tucson, Arizona, United States
Progression Free Survival rate
Time frame: 16 weeks
Objective Response Rate, Disease Control Rate, Progression Free Survival, Overall Survival
Time frame: 18 months
Safety and tolerability as measured by adverse event rates and laboratory evaluations
Time frame: 16 months
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Aurora, Colorado, United States
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Baltimore, Maryland, United States
Massachusetts General Hospital
Boston, Massachusetts, United States
...and 11 more locations