Gonadal Steroid Manipulation and Personality Characteristics: Association With Mood Fluctuations and in Vitro Fertilization (IVF) Outcomes

Tel-Aviv Sourasky Medical Center100 enrolled

Overview

The current study's primary aim is to investigate the association between neuroendocrine fluctuations and mood disorders by monitoring mood states over distinct hormonal phases during in-vitro-fertilization (IVF) treatment. The secondary goal of this study is to explore psychological profiles and coping mechanisms of women undergoing IVF, and to identify the ones that are associated with successful psychological adaptation to the process and a successful biological outcome.

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Mood Disorders

Interventions

IVF procedurePROCEDURE

Eligibility

Sex: FEMALEMax age: 42 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. Admitted for their first or second IVF cycle; 2. Demonstrated sufficient communication skills and level of understanding in the Hebrew language; 3. signed an informed consent; 4. Were under the age of 42; 5. Were not suffering from endometriosis or male factor in patients who underwent testicular sperm extraction (TESE); 6. Were not under psychotherapeutic or psychopharmacological treatment. The accepted indications for the IVF included a female factor, male factor or unexplained infertility. Exclusion Criteria: 1\. All others.

Data from ClinicalTrials.gov

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