Evaluation of Bladder Volumes in Patients Receiving Radiotherapy to the Rectum, Using Kilovoltage Cone-beam Imaging

Royal Marsden NHS Foundation Trust10 enrolled

Overview

The purpose of this study is to implement and access a newly developed bladder filling protocol for patients receiving radiotherapy for rectal cancer using imaging on the treatment unit.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Rectal Cancer

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients receiving radical radiotherapy to rectal malignancies. * Age \> 18 years old * No previous lower GI radiotherapy * Written informed consent according to good clinical practice (GCP) and national / local regulations. Exclusion Criteria: * Patients receiving palliative radiotherapy to rectal malignancies. * Patients receiving radical short course preoperative radiotherapy for rectal malignancies. * Patients unable to give informed consent.

Locations (1)

Royal Marsden NHS Foundation Trust

Sutton, Surrey, United Kingdom

RECRUITING

Outcomes

Primary Outcomes

The percentage of patients who are able to achieve a bladder volume within +/- 30% of planning volume, on all treatment CBCT (cone beam computed tomography) scans

Secondary Outcomes

The per-patient standard deviation of bladder volume throughout the course of radiotherapy

The percentage of patients who are unable to follow the bladder filling protocol at any point during their treatment.

The correlation between bladder volume and small bowel volume planning target volume

Central Contacts

Dr Diana Tait

CONTACT

02086613365 diana.tait@rmh.nhs.uk

Data from ClinicalTrials.gov

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