This trial is conducted in Europe. The aim of this trial is to investigate the safety, tolerability, pharmacokinetics (exposure of drug) and pharmacodynamics (effect) of NNC126-0083 compared to Norditropin® SimpleXx® and placebo in healthy volunteers
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
56
One of five dose levels administered subcutaneously (under the skin)
One of two dose levels, followed by NNC126-0083, administered subcutaneously (under the skin)
Placebo comparator
Novo Nordisk Investigational Site
Hvidovre, Denmark
Number of adverse events
Time frame: after administration of a single dose of NNC126-0083
Area under the curve (AUC) (0-168h) after a single dose of NNC 126-0083
Time frame: 0-168 hours after trial drug administration
Number of injection site reactions
Time frame: after administration of a single dose of NNC126-0083 and after single dose of Norditropin® SimpleXx®
IGF-I (Insulin-like Growth Factor I) levels
Time frame: after ascending single doses of NNC126-0083 and a single dose of Norditropin® SimpleXx®
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
One of three dose levels administered subcutaneously (under the skin)
One of two dose levels, followed by placebo, administered subcutaneously (under the skin)