Effect of Different Protein Diets on Glucose and Insulin Metabolism and Substrate Partitioning

Maastricht University Medical Center12 enrolled

Overview

The purpose of this study is to determine whether different protein diets affects glucose and insulin metabolism and substrate partitioning.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

Conditions

Insulin Glucose Metabolism

Interventions

ControlDIETARY_SUPPLEMENT

Diet consists of 15 En% dairy protein and low GI, 55 En% carbohydrates and 30 En% fat

High dairy proteinDIETARY_SUPPLEMENT

Diet consists of 25 En% dairy protein and low GI, 55 En% carbohydrates and 30 En% fat

vegetable proteinDIETARY_SUPPLEMENT

Diet consists of 15 En% vegetable protein and low GI, 55 En% carbohydrates and 30 En% fat

Eligibility

Sex: MALEMin age: 18 YearsMax age: 35 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * BMI: 18.5-25 kg/m2 (lean) * Gender: Male * Age: \<35 years * Caucasian Exclusion Criteria: * Elevated fasting blood glucose level * Lactose intolerant * Diabetes Mellitus * Hypertension (systolic/diastolic blood pressure) * Hypotension (systolic/diastolic blood pressure) * Cardiovascular diseases * Asthma and other obstructive pulmonary diseases

Outcomes

Primary Outcomes

Glucose and insulin metabolism (24 h)

Time frame: 24 h

Secondary Outcomes

Substrate partitioning and metabolic markers

Time frame: 24 h

Data from ClinicalTrials.gov

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