Protein Hydrolyzation and Glycemic Control

Maastricht University Medical Center

Overview

The insulinotropic effects of protein hydrolysate/amino acid ingestion have been shown to regulate blood glucose homeostasis in both type 2 diabetes patients and normoglycemic controls. The objective of the study is to investigate the optimal dose of such an insulinotropic mixture.

Study Type

INTERVENTIONAL

Purpose

BASIC_SCIENCE

Masking

DOUBLE

Conditions

Diabetes

Interventions

Protein hydrolyzationDIETARY_SUPPLEMENT

Eligibility

Sex: MALEMin age: 40 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Male * Age between 40 and 70 years * Oral blood glucose lowering medication * BMI \< 35 kg/m2 Exclusion Criteria: * Exogenous insulin use * Cardiac disease (any cardiac event in the last 5 years) * Diabetic complications (microvascular complications, microalbuminuria: albumin:creatinine ratio \>2,5)

Locations (1)

Maastricht University Medical Center+

Maastricht, Limburg, Netherlands

Outcomes

Primary Outcomes

Glucose and insulin homeostasis.

Secondary Outcomes

Plasma amino acid profiles

Data from ClinicalTrials.gov

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