Study Evaluating The Efficacy Of A Novel Ibuprofen Formulation On Fever In Patients With An Uncomplicated Acute Infection

Time-weighted Sum of The Temperature Differences From Baseline Through Hour 4 and Hour 8 (STEMPD 0-4 and STEMPD 0-8)

STEMPD 0-4 and STEMPD 0-8 were defined as the time-weighted sum of temperature differences over 4 hours and 8 hours, weighted by the time elapsed between each 2 consecutive time points. Temperature difference was defined as baseline temperature minus post-baseline temperature at each time point, where positive value indicated improvement in body temperature.

Time frame: 0 to 4, 0 to 8 hours

Change From Baseline in Temperature at Hours 0.25, 0.5, 1, 2, 4, 6 and 8

Change from baseline in temperature was calculated as baseline temperature minus post-baseline temperature at each time point, where positive value indicated improvement in body temperature.

Time frame: Baseline, 0.25, 0.5, 1, 2, 4, 6, 8 hours

Time to Treatment Failure

Median time of dropping out of the participants from the study due to lack of efficacy or use of rescue medication, whichever comes first.

Time frame: 0 to 8 hours

Cumulative Percentage of Participants With Treatment Failure

Percentage of participants who withdrew from the study due to lack of efficacy or received rescue medication.

Time frame: 0.25, 0.5, 1, 2, 4, 6, 8 hours