Pulmonary arterial hypertension (PAH) is a severe pulmonary vascular affection, which treatment has evolved in the last few years, improving quality of life. However, adherence to treatment has not been assessed in such patients. The investigators developed a collaborative care model involving clinical pharmacists in PAH. The objective of this work is to evaluate the impact of such model of care on medication errors and adverse events, quality of life and clinical criteria. This randomized multicentre controlled study will include approximately 100 PAH patients (NYHA II to IV). After inclusion, patients will receive either collaborative care including consultations with specialized pharmacist and nurse, or classic follow-up. Each patient will be followed during 18 months from the date of inclusion. The investigators hope to show the positive impact of a collaborative care model in PAH. More specifically, the investigators aim to show the interest of long-term patient education to improve patient safety related to drugs, but also their quality of life, and have preliminary data about usual clinical criteria.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Masking
SINGLE
Enrollment
101
Pharmaceutical care of patients with PAH
Clinical and biological data, treatment, medication errors and ADEs
CHU Bordeaux
Bordeaux, France
CHU Brest
Brest, France
Hopital Antoine Beclere
Clamart, France
Clinical Research Center Inserm CIC03 - Grenoble University Hospital
Grenoble, France
CHU Grenoble
Grenoble, France
CHU de Lille
Lille, France
CHU Nantes
Nantes, France
CHU de Nice
Nice, France
CHU Rouen
Rouen, France
CHU Strasbourg
Strasbourg, France
...and 1 more locations
Medication-related problems
Medication errors (assessed by using the tool developped by the French Society for Clinical Pharmacy) and adverse drug reactions
Time frame: 18 months
Patient Satisfaction with medication
Comparison between the SATMED-Q(R) score at 18 months between the two groups
Time frame: 18 months
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