Residual post-inflammatory hyperpigmentation (PIH)from acne is disturbing to individuals with skin of color. Finacea has been anecdotally known to be beneficial in resolving PIH related to acne vulgaris. However, it has not been clinically tested for this purpose. The current study will investigate the efficacy and safety of Finacea in the treatment of acne vulgaris and PIH.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
20
Apply sparingly to the face twice a day (morning and night). Massage gently into the skin until vanishing. Approximately 0.5g (2.5cm strip) is sufficient for the entire facial area.
DermResearch, PLLC
Louisville, Kentucky, United States
Percentage of Participants With Improvement in Acne IGA (Investigator Global Assessment)
IGA Assessments at each visit (baseline and follow up) based on a 6 point scale (0= clear through 5 = very severe). Improvement is defined as at least a 1 point improvement.
Time frame: Baseline to 16 weeks
Percentage of Participants With Improvement in the IGA of Post Inflammatory Hyperpigmentation(PIH)
IGA for PIH assessed on a 7 point scale (0= clear through 6 = severe) with at least a two point improvement
Time frame: Baseline to16 weeks
Percentage of Participants With an Improvement in Post Inflammatory Hyperpigmentation (PIH) % Distribution
The % distribution of PIH, evaluated on a scale of 0 = no PIH through 6 = greater than 50%
Time frame: Baseline to 16 weeks
Percentage Change in Total Lesion Counts
Total lesions including inflammatory lesions (papules, pustules, nodules) and non-inflammatory lesions (open and closed comedones).
Time frame: Baseline to 16 weeks
Tolerability Assessments as Measured by the Number of Participants With Side Effects
Tolerability parameters assesssed by the presence and degree of peeling, erythema, dryness, oiliness, burning and pruritus
Time frame: 16 weeks
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.