To Evaluate the Dose Response of 3 Doses of Euphorbia Prostrata in Patients With First and Second Degree Hemorrhoids

Inclusion Criteria: * Adult subjects who are able to understand nature, significance and scope of the clinical trial and express their will accordingly and agreeing to participate in the study by giving written informed consent. * Male or female subjects, at least 18 years of age with a diagnosis of internal hemorrhoids (first and second degree) confirmed by proctoscopic examination and suffering from an uncomplicated and untreated acute attack (defined as acute onset of per rectal bleeding within 3 days of inclusion into the study, with at least one of the symptoms viz. pain, tenesmus, pruritus and anal discharge). * Except internal hemorrhoids (first and second degree), the subjects are judged to be in good general health, based on medical history, physical examination, and laboratory screening tests. Exclusion Criteria: * Pregnant and lactating women and women in post-partum period of up to 6 weeks. * Women of child bearing potential who do not agree to remain abstinent or use medically acceptable methods of contraception during the study therapy and for 4 weeks after the end of study therapy. * Subjects who have been previously enrolled in a study involving E. prostrata Dry Extract * Subjects with a history of permanent anal prolapse and/or anal fistula * Subjects with associated anal fissures and/or infective anal pathology. * Subjects with previous history of surgery for anorectal disease (within 5 years) or any other procedures (including but not limited to injection sclerotherapy, rubber band ligation, photocoagulation, cryotherapy etc) within 2 year of enrolment into the trial. * Subjects who, in the opinion of the investigator, are mentally incapacitated such that informed consent cannot be obtained. * Subjects with clinically significant co-morbid condition that in the opinion of the investigator could affect the efficacy and safety outcome of the study. * Subjects with clinically significant laboratory values for hemoglobin, total leukocyte count, differential count, bleeding time, clotting time, PT/INR, aPTT/control, platelet count, SGOT, SGPT, alkaline phosphatase, total bilirubin, random blood sugar, serum cholesterol, blood urea, serum creatinine and urine routine and microscopic examination. * Treatment with any of the following at inclusion or in the previous one month venotropic, anticoagulant, and anti platelet agent. Subjects on aspirin up to 160 mg for cardiovascular indication will not be excluded from the trial. * Treatment with any of the following at inclusion or in the previous one week anti-inflammatory and analgesic agent. * Other chronic medications not being used at a stable dosage for at least 2 weeks. * Subjects who are current users of illicit drugs including "recreational use" or with a history of drug abuse within the past 5 years. * Subjects who have donated a unit of blood or plasma or participated in another clinical study with an investigational agent within the last 12 weeks