NAVA used the electrical activity of the diaphragm (EAdi) to initiate and deliver in proportion of an inspiratory assistance. During inspiration, EAdi signal occurred earlier than airflow or pressure variations in the airway. The investigators hypothesized that NAVA improved patient-ventilator synchrony and reduced inspiratory workload as compared with pressure support ventilation delivered at two different cycling criteria (25 and 50 %).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
16
Assisted mechanical ventilation according to the electrical activity of the diaphragm recorded with a 16-FR naso-gastric tube mounted with EMG electrodes
Varying the cycling criterion according to the percentage of peak inspiratory flow
Hopital Paul Desbief
Marseille, France
Fondation Hôpital Ambroise Paré
Marseille, France
Inspiratory muscle workload as reflected by the diaphragmatic Pressure Time Product (PTPdi)
Time frame: 5 minutes
Ineffective inspiratory effort
Time frame: 5 minutes
Dynamic intrinsic PEEP
Time frame: 5 minutes
Arterial blood gases
Time frame: 20 minutes
Trigger delay
Time frame: 5 minutes
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