Trial of Adjuvant Sutent for Patients With High Risk Urothelial Carcinoma After Neoadjuvant Chemotherapy and Cystectomy

Inclusion Criteria: * Histologic diagnosis of bladder carcinoma (\>50% urothelial carcinoma) * Prior treatment with at least one cycle of platin-based neoadjuvant chemotherapy * Prior treatment with radical cystectomy revealing pT3NxM0 or pTanyN+M0 * ECOG performance status of 0-1 (Appendix 2). * No evidence of metastases within 4 weeks of registration * Adequate organ and marrow function obtained within 14 days of registration Exclusion Criteria: * Severe or uncontrolled acute or chronic medical or psychiatric condition * Prior antiangiogenic therapy * Prior pelvic radiation for bladder cancer