A Two Part Trial Investigating an Anti-obesity Drug in Overweight/Obese Male and Female Healthy Volunteers

Inclusion Criteria: * FOR TRIAL PART 1, THE FOLLOWING APPLIES: * Informed consent must be obtained before any trial-related activities. Trial-related activities are any procedures that would not have been performed during the normal management of the subject * Overweight/obese males: Body Mass Index (BMI) between 27.0 to 39.0 kg/m2 * Good general health * FOR TRIAL PART 2, THE FOLLOWING APPLIES: * Informed consent must be obtained before any trial-related activities. Trial-related activities are any procedures that would not have been performed during the normal management of the subject. * Obese male and female subjects: Body Mass Index (BMI) between 30.0 to 39.0 kg/m2 * Good general health. Exclusion Criteria: * Aggressive diet attempts within the last 3 months * Current or history of treatment with medications that may cause significant weight gain * History of major depressive disorder or history of a suicide attempt or history of any suicidal behaviour * History of eating disorders * Any weight change of 5 kg (11 pounds) in the last 3 months * Tobacco use * History of alcoholism or drug/chemical abuse