This study will investigate the absorption, distribution, metabolism and excretion after giving 2000 mg 14C-SLV334 via a 1-hour infusion. The absolute bioavailability will also be determined.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
6
2000 mg via i.v. solution
S334.1.004 - Site 1
Zuidlaren, Netherlands
Percentage excreted in urine and feces
Time frame: 16 days
metabolic profile SLV334
Time frame: 16 days
AUC, CL, lambda z, Cmax, t1/2, tmax and Vss
Time frame: 16 Days
adverse events
Time frame: 16 days
vital signs
Time frame: 16 days
ECG
Time frame: 16 days
Laboratory safety variables
Time frame: 16 days
Physical examination
Time frame: 16 days
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