Effect of Ginkgo Biloba Special Extract LI 1370 on Dual-tasking in Patients With MCI

Inclusion Criteria: * Age 50-85 years * Swiss German or German speaker * Completed elementary school * Impaired executive function (gait speed reduction ≥ 10% under dual-task as compared to normal walking) * No dementia according to International Classifications of Diseases (ICD)-10 and Diagnostic and Statistical Manual of Mental Disorders (DSM)-IV. * Cognitive decline (self/informant report or objective task) * Preserved basic activities of daily living and minimal impairment in complex instrumental functions * Written informed consent and nihil obstat Exclusion Criteria: * Current drug treatment with Warfarin-like drugs (Coumarins or Clopidogrel), however, acetylsalicylic acid 100mg and 300mg is permitted * Current intake of GBE or during the last 6 months * Known hypersensitivity to GBE or its constituents * Regular intake of antipsychotic, anxiolytic or sedative drugs(allowed if clinically stable for at least the past 3 months while under treatment) * Concomitant gait-relevant disorders: severe cardio/pulmonary/cerebron -vascular disorders, bleeding diathesis, polyneuropathy and severe orthopedic disorders, organic cerebral disease epilepsy, low vision * Severe medical conditions (e.g. chronic renal insufficiency, severe hepatic disorders,cardio-vascular disease, uncontrolled hypertension, peptic ulcer, malignoma) * Participation in another clinical intervention study within the last 2 months * Use of walking aid * Normal walking speed is \< 100cm/s