The purpose of this study is to determine if BMS-770767 is safe, well tolerated, measure its levels in the blood (pharmacokinetics), and measure the levels of chemicals (biomarkers) that may be affected by this drug (pharmacodynamics) in a type 2 diabetes patient population
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
76
Capsule, Oral, 15mg, Active, Daily, 28 days
Capsule, Oral, 50mg, Active, Daily, 28 days
Capsule, Oral, 150mg, Active, Daily, 28 days
Marina Raikhel, Md
Lomita, California, United States
Nevada Alliance Against Diabetes
Las Vegas, Nevada, United States
Fasting Plasma Glucose Improvement
Time frame: Within seven days following dosing
Mean daily glucose (3-day 7 pt-fingerstick)
Time frame: Within 28 days following dosing
Four (4)-hour post-prandial glucose AUC
Time frame: Within 28 days following dosing
HbA1C
Time frame: Within 28 days following dosing
Lipid profiles
Time frame: Within 28 days following dosing
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Capsule, Oral, 50mg BID, Active, Daily, 28 days
Capsule, Oral, 0mg, Daily, 28 days
Tablet, Oral, ≥ 1500mg, Active, Daily, 28 days
Local Institution
Caboolture, Queensland, Australia
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Meadowbrook, Queensland, Australia
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Daw Park, South Australia, Australia
Local Institution
Geelong, Victoria, Australia
Local Institution
Nedlands, Western Australia, Australia
Local Institution
Winnipeg, Manitoba, Canada
Local Institution
Mount Pearl, Newfoundland and Labrador, Canada
Local Institution
Brampton, Ontario, Canada
...and 8 more locations