The purpose of this research study is to evaluate the effectiveness of two different types of topical acne medication. This study will help to determine if one combined medication results in better acne improvement than two separate medications for acne.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
26
applied once daily for 12 weeks
Topical clindamycin applied each morning for 12 weeks
Tretinoin 0.025% cream each evening for 12 weeks
Wake Forest University Health Sciences, Dermatology
Winston-Salem, North Carolina, United States
Measured Adherence to ZIANA Gel or Generic Topical Clindamycin 1% Gel Each Morning Plus Generic Topical Tretinoin 0.025% Cream Each Evening in Subjects With Mild to Moderate Acne
Percentage of prescribed doses taken as measured by a Medication Event Monitoring System (MEMS) cap
Time frame: 12 weeks
The Change (Dynamic Assessment) From Baseline to Week 12 (or End of Treatment) in Total Acne Lesion Count
Time frame: Baseline to 12 weeks
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