It has been previously demonstrated that the risk for the development of knee osteoarthritis is increased after both meniscus tear and meniscectomy. However, it is still unclear whether this is due to the meniscus tear per se, the surgery, or whether the development of knee osteoarthritis is completely independent of the two. Accordingly, the aim of the study is to investigate the effect of arthroscopic partial meniscectomy on the development of knee osteoarthritis 2 to 10 years after the procedure.
It has been previously demonstrated that the risk for the development/progression of knee osteoarthritis is increased after both meniscus tear and meniscectomy. However, it is still unclear whether this is due to the meniscus tear per se (i.e., adverse mechanical effect on knee cartilage), the surgery (resection of the meniscus, and subsequent loss of cushion within the knee), or whether the development of knee osteoarthritis is completely independent of the two. Accordingly, the aim of the study is to investigate the effect of Arthroscopic partial meniscectomy on the development of knee osteoarthritis 2 to 10 years after the procedure. Patients included in the study will be randomized into one of two groups: arthroscopic partial meniscectomy and diagnostic arthroscopy (sham-surgery). The presence of knee osteoarthritis will be assessed preoperatively and 2, 5, and 10 years after the operation.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Enrollment
160
Arthroscopic partial meniscectomy of the degenerative tear of medial meniscus
Diagnostic arthroscopy of the knee
Helsinki Central Hospital
Helsinki, Finland
Central Finland Hospital District
Jyväskylä, Finland
Kuopio University Hospital
Kuopio, Finland
Tampere City Hospital
Tampere, Finland
Turku University Hospital
Turku, Finland
Radiological assessment of OA of the knee (Kellgren-Lawrence -classification)
Time frame: 2 and 10 years postoperatively
ACR (The American College of Rheumatology) clinical criteria for Osteoarthritis of the knee
Time frame: 2 and 10 years postoperatively
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