Iodine Content for Diagnostic AccuRacy and Patient Comfort For Individuals Undergoing Cardiac Computed Tomography (CT) Scanning

Inclusion Criteria: * The subject is ≥18 years old. * The subject has typical or atypical chest pain suspected of Coronary Artery Disease (CAD) and is referred for an elective coronary angiography. * The subject must be scheduled to undergo a CATH procedure between 72 hours and 3 weeks of the CCTA procedure. * The subject must not undergo any cardiac interventional treatment between the 2 procedures. * The subject must have a sinus rhythm with stable heart rate of ≤75 beats per minute (bpm) and if heart rate is \>65 bpm, the subject must agree to the use of beta-blocker(s) prior to the CT scan procedure to achieve stable heart rate of ≤65 bpm. Exclusion Criteria: * The subject has an established diagnosis of CAD by a) previous ICA, b) prior myocardial infarction confirmed by electrocardiogram (ECG), or c) prior revascularization (balloon angioplasty, stent placement, or coronary artery bypass grafting (CABG). * The subject has a known allergy to iodinated contrast agent, including but not limited to hives, anaphylactoid or cardiovascular reactions, laryngeal edema and bronchospasm. * The subject has impaired renal function with a serum creatinine level of 1.7 mg/dL (150 μmol/L) or above. * The subject has atrial fibrillation/flutter or any irregular heart rhythm considered by the investigator to interfere with temporal acquisition of cardiac CT images. * The subject has a resting heart rate of \>100 bpm and/or a resting systolic blood pressure of \<100 mm Hg. * The subject has an artificial heart valve(s). * The subject has had prior pacemaker or internal defibrillator lead implantation. * The subject's resting heart rate is \>65 bpm and beta-blocker therapy is contraindicated. * The subject has a contraindication to Verapamil when beta-blocker therapy cannot be administered. * The subject has a contraindication to nitroglycerin. * The subject has evidence of ongoing or active clinical instability.