Study of How Single Rising Doses of SAR161271 Are Absorbed and Act in Patients With Type 1 Diabetes Mellitus (T1DM)

Inclusion criteria: * Patients who have type 1 diabetes mellitus (T1DM) as defined by American Diabetes Association average total insulin dose of \<1.2 U/kg/day * Fasting negative serum C-peptide (\<0.3 nmol/L) * Glycated hemoglobin (HbA1c) \< or = 9% * Stable insulin regimen for at least 2 months before the study * Body weight between 50-110 kg inclusive; body mass index between 18-30 kg/m2, inclusive * Certified as healthy for T1DM by a comprehensive clinical assessment Exclusion criteria: * Any history or presence of clinically relevant (for T1DM) cardiovascular, pulmonary, gastrointestinal, hepatic, renal, metabolic, hematological, neurological, psychiatric, systemic, ocular, or infectious disease, or signs of acute illness, or major diabetic complications such as diabetic retinopathy. * Blood donation, any volume, within 1 month before inclusion. * Presence or history of drug hypersensitivity, or allergic disease diagnosed and treated by a physician * Regular use of any medication other than insulins in the last month before study start with the exception of thyroid hormones, metformin, lipid-lowering and antihypertensive drugs * Positive reaction to any of the following tests: hepatitis B surface (HBs) antigen, anti-hepatitis C virus (anti-HCV) antibodies, anti-human immunodeficiency virus (HIV) 1 antibodies, anti-HIV2 antibodies. The above information is not intended to contain all considerations relevant to a patient's potential participation in a clinical trial.