Glycemic Index and Polyphenol Bioavailability of Potatoes

Guelph Food Research Centre10 enrolled

Overview

The purpose of this study is to determine the glycemic index of four varieties of potatoes and to determine the bioavailability of polyphenols contained in these potatoes.

Ten healthy persons will have a fasting blood sample drawn and asked to randomly consume a 50g glucose drink (2 occasions), or 50g carbohydrate equivalent of cooked purple, red, yellow and white potatoes. Further blood samples will be obtained at 15,30, 45, 60, 90, 120, 180, 240 mins. Bloods from the first 2 hours will be analyzed for glucose and insulin to determine the glycemic response. Hourly blood samples will be analyzed for polyphenol to determine the bioavailability of polyphenols from the different potato variety. Urine samples will be collected before ingestion of the food items and again at 4 hours, and will be used to determine polyphenol bioavailability.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Diabetes Insulin Resistance

Interventions

Glycemic response to different varieties of potatoesOTHER

the glycemic response top 50g available carbohydrates from 4 potato varieties will be compared to a 50g glucose standard

Eligibility

Sex: ALLMin age: 18 YearsMax age: 50 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * healthy, non-smoker on no medication * normal glucose tolerance * willing to have a catheter inserted in forearm Exclusion Criteria: * abnormal glucose tolerance * abnormal BMI * on medication for a chronic disorder

Locations (1)

Nutrasource Diagnostic Inc

Guelph, Ontario, Canada

Outcomes

Primary Outcomes

Glycemic response

Time frame: 2 hrs

Secondary Outcomes

Bioavailability of polyphenols from potatoes

Time frame: 4 hours

Data from ClinicalTrials.gov

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