Ramipril 10 mg/Day Prevention

Inclusion Criteria: * History of coronary artery disease, * Stroke * Stable heart failure * Peripheral vascular disease, or diabetes with at least one other cardiovascular risk factor (hypertension, elevated total cholesterol levels, low high-density lipoprotein cholesterol levels, cigarette smoking, or documented microalbuminuria). Exclusion Criteria: * Non stabilized or NYHA grade IV heart failure patients * Hemodynamically significant primary valvular or outflow tract obstruction (eg. mitral valve stenosis, asymmetric septal hypertrophy, malfunctioning prosthetic valve) * Constrictive pericarditis. * Complex congenital heart disease. * Syncopal episodes presumed to be due to uncontrolled life-threatening arrhythmias (asymptomatic cardiac arrhythmias including ventricular tachycardia are not an exclusion criterion). * Planned cardiac surgery or angioplasty within 3 months (patient may be reconsidered for the trial after the procedure). * Cor pulmonale. * Heart transplant recipient. * Significant renal disease defined as: * Renal artery stenosis; * Creatine clearance \<0.6 ml/second or serum creatinine≥ 200 mEq/L (≥2.26 mg/dl) * Overt nephropathy: ≥1 plus proteinuria on dipstick or urinary albumin excretion \> 200 micrograms/minute (300 mg/24 hrs) * Hyperkalemia; K\>5.5 mEq/L. * Patient is simultaneously taking another experimental drug. The above information is not intended to contain all considerations relevant to a patient's potential participation in a clinical trial.