The main objective of the study is to estimate the proportion of children, born between the 06/04/2004 and the 17/004/2008, living around Neufchatel en Bray, vaccinated by MenBVac, with a serum bactericidal activity against B:14,P1-7,16 clone related to a protection (\>= 4), before the first vaccination (T0), after the second MenBvac vaccination (6 weeks after the second vaccination), before the third MenBvac vaccination and after the third MenBvac vaccination (6 weeks after the second vaccination) and one year after the third menBvac vaccination.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
218
* First blood sample prior to vaccination with MenBVac * First and second doses of MenBVac * Second blood sample 6 weeks after the second dose of the vaccine * Third blood sample immediatly before the third dose of the vaccine * Third dose of MenBVac * Fourth blood sample 6 weeks after the third dose of the vaccine * Fifth blood sample one year after the third dose of the vaccine
Maison Du Département
Neufchâtel-en-Bray, France
assessment of natural Immunity with measure of percent of children who have hSBA title >= 4 at TO. assessment of antibodies blood persistence during measurement of percent of children who have hSBA title >= 4
Time frame: 18 months
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