Transversus Abdominus Plane Block

Mayo Clinic21 enrolled

Overview

Transversus Abdominus Plane (TAP) block may reduce need for postoperative pain medications in patients undergoing laparoscopic hand assisted nephrectomy. Our hypothesis is that the TAP block will result in a significant reduction in pain scores and morphine requirements in the active group.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

DOUBLE

Enrollment

Conditions

Nephrectomy

Interventions

TAP block placement with placeboPROCEDURE

20 ml of normal saline (placebo)

Placement of block with ropivacainePROCEDURE

20 ml of 0.5% ropivacaine hydrochloride

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients who are ≥ 18 and ≤ 80 years of age. * Patients scheduled to undergo hand assisted laparoscopic removal of a single kidney for either tumor or living donor transplantation. Exclusion Criteria: * Patients scheduled to undergo an open procedure for nephrectomy * Patients who are converted from hand assisted laparoscopic surgery to open surgery due to intraoperative complications. * Bilateral nephrectomy * Pregnant or lactating patients * Patients unable or unwilling to provide informed consent * Patients unable to comprehend the use of a visual analog scale * Patients desiring preemptive antiemetics * Opioid tolerance * Allergy to amide local anesthetics or any of the study drugs (morphine). * Contraindication to regional nerve block (bleeding disorder, infection at site of block) * Patients with history of dementia

Locations (1)

Mayo Clinic

Jacksonville, Florida, United States

Outcomes

Primary Outcomes

Determine if TAP block is a viable alternative to PCA narcotics for the control of pain after hand-assisted, laparoscopic nephrectomy.

Time frame: 24 hours postoperatively

Secondary Outcomes

TAP block with ropivacaine will lead to equivalent or better results with regard to the following outcomes:pain scores, nausea, vomiting, sedation, request for PCA, discontinuation of Foley catheter, discharge from the hospital

Time frame: 24 hours postoperatively

Data from ClinicalTrials.gov

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