The Effect of Fluorouracil Implants Regional Chemotherapy During the Surgical Treatment for Early Stage Hepatocellular Carcinoma

Inclusion Criteria: * Histological diagnosis of stage I hepatocellular carcinoma * Child-Pugh class A, B * Radical resection is feasible * Patients with adequate renal, hepatic, and hematologic function * Written informed consent Exclusion Criteria: * Allergic to chemotherapy drugs * No measurable lesion * Receive chemotherapy, radiotherapy or biotherapy within 30 days prior to enrollment * Evidence of serious infection * Renal or hepatic dysfunction, significant cardiovascular disease * Pregnant or lactating women