Dietary Supplements and Aging Muscle

University of Alabama at Birmingham36 enrolled

Overview

The purpose of this study is to determine whether older adults (ages 65-89) who consume the dietary supplement Juven (Abbott Laboratories) versus placebo for 6 months will demonstrate increases in fat-free mass, muscle volume,and physical function.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

QUADRUPLE

Enrollment

Conditions

Sarcopenia

Interventions

JuvenDIETARY_SUPPLEMENT

Participants in the treatment arm will be asked to consume 2 packets of Juven drink mix each day for a period of six months.

JuvenDIETARY_SUPPLEMENT

Participants in the placebo arm will be asked to consume two packets of an orange-flavored drink mix each day for a period of six months.

Eligibility

Sex: ALLMin age: 65 YearsMax age: 89 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Ages 65-89 * Ambulatory Exclusion Criteria: * Cognitive impairment * History of renal or hepatic disease * History of hypotension * History of peripheral artery disease * Uncontrolled hypertension * Uncontrolled diabetes * Self-reported claustrophobia * Current smoker * Steroid or androgen use with the previous 3 months * Individuals with pacemakers and defibrillators

Locations (1)

University of Alabama at Birmingham

Birmingham, Alabama, United States

Outcomes

Primary Outcomes

Fat-free mass as determined by a four-compartment model of body composition

Time frame: Baseline, 3-months, 6-months

Secondary Outcomes

Appendicular lean mass as determined by dual energy X-ray absorptiometry

Time frame: Baseline, 3-months, 6-months

Muscle volume as determined by magnetic resonance imaging

Time frame: Baseline and 6-months

Physical function as determined by questionnaire and a battery of physical performance tests

Time frame: Baseline and 6 months

Data from ClinicalTrials.gov

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