Short Course of Amoxicillin for Erysipelas

Inclusion Criteria: * Males and females ≥ 18 years of age * First episode of erysipelas of a lower leg defined as * acute well delineate inflammation than had lasted less than 5 days * T°≥ 38°5 at least once during the past 5 days or chills. * Score ≥3 : oedema, erythema, pain each scored from 0 to 3 : 0= none, 1= moderate, 3= severe * Written informed consent provided by the patient * available health insurance * accept conditions of the trial Exclusion Criteria: * Erysipelas for more than 5 days * Score \< 3 * Septic shock * Clinical signs of necrotizing cellulitis or fasciitis, bullous lesions related to necrosis, purpuric lesions or superficial cutaneous necrosis. * Past history of erysipelas of the same lower leg * Erysipelas not on the lower leg * Bilateral erysipelas * Bite occuring during the preceding 7 days. * Diabetic foot * patients who have previously received systemic antibiotherapy within the last 5 days (except one or two doses within last 24 hours) * History of any hypersensitivity or allergic reaction to beta-lactam drugs * Known renal or Hepatic failure * Known HIV infection * Female patients who are pregnant, lactating (breast milk feeding), or who are of child bearing potential and not using an acceptable method of birth control * Impossibility to stop immunosuppressive treatment, systemic corticosteroids or nonsteroidal anti-inflammatory drugs. * Severe gastrointestinal disease, dysphagia or any pathology preventing oral administration of treatment. * Denied to sign written informed consent * Unable or unwilling to adhere to the study-specified procedures and restrictions * Evolutive cancer under treatment