Postoperative Analgesia After Laparoscopic Living Donor Nephrectomy

Oslo University Hospital80 enrolled

Overview

The aim of the study is to investigate if perioperative administration of pregabalin vil reduce postoperative pain and the postoperative need for intravenous opioids compared with todays standard treatment which consist of paracetamol, corticoids and ketobemidone. In addition potential sideeffects as sedation and effect on cognitive function will be recorded.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Living Donors

Interventions

PregabalinDRUG

150 mg x 2 daily for 2 days

Sugar pillDRUG

1 tablet x 2 daily, for 2 days

Eligibility

Sex: ALLMin age: 18 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * \>18, \< 75 years * healthy patients accepted for laparoscopic living donor nephrectomy Exclusion Criteria: * not familiar to the Norwegian language (spoken and written) * allergic to one or more of the medication given in the study

Locations (1)

Oslo Universitetssykehus, Rikshospitalet

Oslo, Norway

Outcomes

Primary Outcomes

Opioid consumption in milligrams Pain Score given as Numeric Rating Scale (NRS)

Time frame: Daily troughout the hospital stay, approx. 6 days

Secondary Outcomes

Sedation and cognitive function

Time frame: Daily troughout the hospital stay, approx. 6 days

Data from ClinicalTrials.gov

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