Treatment of Locally Advanced Non-Small Cell Lung Cancer (NSCLC)

Inclusion Criteria: * biopsy proven non-squamous NSCLC with unresectable stage IIIA or dry IIIB disease. * FEV1 \>/= 1 liter * ECOG PS 0 or 1 * Able to swallow and absorb enterally * Measurable disease per RECIST 1.1 * Adequate organ and marrow function including calculated creatinine clearance \>/= 60 mL/min hepatic enzymes and alk phos \</= 2.5 X ULN. Exclusion Criteria: * Chemotherapy or radiotherapy \</= 4 weeks prior to registration (6 weeks for nitrosureas) * Active bleeding * Known brain mets * Prior thoracic radiotherapy that would lead to overlap with current radiation field. * More than 10% weight loss in 6 months. * Pancoast tumors, supraclavicular or contralateral hilar lymph node involvement * Known HIV positive * Prior treatment with an HDAC inhibitor