Safety and Tolerability of LIM-0705 in Healthy Male Subjects

Inclusion Criteria: * Male age 18-50 * Patient in good health as deemed by pre-study exam and history * BMI 20-30 kg/sq. meter * Absence of tremors * Must be willing to remain in confinement for 17 days/16 nights * Systolic BP 90-140 mmHg, diastolic BP 50-90 mmHg, resting HR 45-90 bpm * Subject must be non-smoker or willing to abstain from smoking day -4 through day 30. * Subject must abstain from alcohol, grapefruit,and caffeine-containing beverages starting Day -2 through Day 30. * Subjects must use double-barrier contraception through course of study + 90 days following study Exclusion Criteria: * Allergy to red wine or onions * Strict vegetarians * Use of any non-study medication * Use of chemotherapy within 5 years prior to Screening visit * Use of any dietary aids * Difficultly swallowing oral medications * cognitive or psychiatric disorders