Altered Faecal Protease Activity in Irritable Bowel Syndrome Patients in China

Xi'an Jiaotong University60 enrolled

Overview

Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder haracterised by abdominal pain or discomfort associated with altered bowel habits,while the mechanism is still not understood.Recent advances have conceptualized the faecal supernatants of diarrhoea-predominant IBS have a substantially higher serine protease activity, while in china,almost no studies have reported about protease activity in IBS.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Irritable Bowel Syndrome

Eligibility

Sex: ALLMin age: 18 YearsMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patients fulfilling the Rome III criteria for IBS participated in the study - Exclusion Criteria: * Organic gastrointestinal disorders were excluded by detailed blood and stool analyses, serological assays and colonoscopy.

Data from ClinicalTrials.gov

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