Influence of Intracranial Lesions on Bispectral Index

University Medical Center Groningen40 enrolled

Overview

The purpose of this study is to assess whether BIS values at return of consciousness are different in patients with or without brain tumors.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Supratentorial Brain Tumor

Interventions

BIS values at return of consciousness in patients + predicted and measured propofol plasma concentrationsDEVICE

Difference between left- and rightsided BIS values in patients with supratentorial brain tumor during course and Comparison between predicted and measured propofol plasma concentrations during course of the study

BIS values at return of consciousness in patients + predicted and measured propofol plasma concentrationsDEVICE

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients undergoing elective craniotomy for removal of frontal or frontotemporal brain tumors. * Control group: Neurosurgical patients without intracranial pathology. Exclusion Criteria: * Patient refusal * Significantly increased intracranial pressure * Uncontrolled arterial hypertension * Significant coronary artery disease * Anticipated difficult airway * Decreased level of consciousness * Existing motor weakness dominant arm/hand * Impaired hearing * Nausea, vomiting

Locations (1)

University Medical Center Groningen

Groningen, Provincie Groningen, Netherlands

Outcomes

Primary Outcomes

Bilateral BIS values at return of consciousness in patients with and without supratentorial brain tumor.

Time frame: one year

Secondary Outcomes

Time frame: one year

Data from ClinicalTrials.gov

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