Efficacy of Ultrasound Contrast Agent to Assess Renal Masses

University Health Network, Toronto167 enrolled

Overview

Patients with an incidentally discovered small renal masses (SRM) \< 4 cm in diameter are included. All patients will undergo biopsy for tissue diagnosis. Most patients will be followed by imaging. Study intervention includes low MI US to be performed following both bolus and infusion injection of Definity contrast. Presence and absence of vascularity, pattern of vascularity, and TIC values will be correlated with the final pathology to find features differentiating benign from malignant masses.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

167

Conditions

Renal Cell Carcinoma

Interventions

DefinityDRUG

Definity is the contrast agent which is going to be injected in a bolus and infusion forms during the ultrasound performance.

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with newly diagnosed Renal mass \< 4 cmm, who are going to undergo diagnostic CT, MRI or biopsy.

Locations (1)

Toronto General Hospital

Toronto, Ontario, Canada

Outcomes

Primary Outcomes

biopsy

Time frame: 12 to 18 months

Data from ClinicalTrials.gov

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