Teriparatide for Improved Knee Prosthesis Fixation

University Hospital, Linkoeping60 enrolled

Overview

The investigators will study how well knee joint prostheses become fixed to the bone when patients get teriparatide, compared to placebo. Measurements will use high resolution 3D radiography (radiostereometry, RSA).

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

QUADRUPLE

Enrollment

Conditions

Osteoarthritis of the Knee

Interventions

teriparatideDRUG

Eligibility

Sex: ALLMin age: 60 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Osteoarthritis of the knee planned for prosthesis surgery Exclusion Criteria: * Poor health, drugs affecting bone metabolism.

Locations (1)

Motala hospital

Motala, Sweden

Outcomes

Primary Outcomes

Migration as measured by RSA maximal total point motion.

Time frame: 2 years

Data from ClinicalTrials.gov

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