Outcomes Study of Late Effects After Proton RT for Pediatric Tumors of the Brain, Head, and Neck

Inclusion Criteria: * Estimated \>5 cc of the brain tissue to receive \>5 CGE radiation * Patient must be less than 21 years of age at time of consent. * Patients that require localized and craniospinal irradiation. * Patients and/or patient parent must complete baseline Quality of Life Questionnaire as applicable by patient age group. Exclusion Criteria: * Prior radiation therapy. * Evidence of metastases outside the central nervous system.