Transcranial Doppler Ultrasonography and Brain Death

Institut d'Anesthesiologie des Alpes Maritimes44 enrolled

Overview

In France the diagnosis of brain death relies on electroencephalography (EEG) or cerebral angiography. Concerning the latter a time of 6 hours is mandatory between the clinical diagnosis and the realization of the cerebral computed tomography (CT) angiography. Transcranial doppler (TCD) is not recommended in the french guidelines for the diagnosis of brain death. In other countries, some flow patterns allow to confirm the diagnosis of brain death. The hypothesis of our study is that TCD could shorten the time between the clinical diagnosis of brain death and the realization of the CT angiography.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Brain Dead

Interventions

Transcranial dopplerOTHER

A TCD is performed on all cerebral arteries (mean cerebral arteries, anterior cerebral arteries, basilar trunk, vertebral arteries and carotid arteries) until a flow pattern compatible with brain death is found

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * brain death patients Exclusion Criteria: * craniectomy * post anoxia encephalopathy * no TCD performed before the clinical diagnosis of brain death * transtemporal approach impossible

Locations (1)

Centre Hospitalier Universitaire de Nice

Nice, France

Outcomes

Primary Outcomes

Time between clinical diagnosis of brain death and realization of CT angiography

Time frame: the outcome is assessed when the CT angiography is performed

Secondary Outcomes

Number of CT angiography required for the diagnosis of brain death

Time frame: the outcome is measured until the diagnosis of brain death is confirmed

Data from ClinicalTrials.gov

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