Pharmacodynamics of Lorelin Depot (Leuprorelin Acetate - Bergamo) Compared to Lupron Depot ® (Leuprorelin Acetate - Abbot)

Inclusion Criteria: 1. Accept the Informed Consent. 2. Subjects of research males aged 40 to 45 years; 3. Subject of research with body mass index greater than or equal to 19 and less than or equal to 30; 4. Be considered healthy, from the analysis of the clinical history and medical examination; 5. Laboratory tests with results outside the values considered normal, but not considered clinically relevant. Exclusion Criteria: 1. Have donated or lost 450 mL or more of blood in the three months preceding the study; 2. Have participated in any experimental study or have taken any experimental drug in the last three months prior to the start of the study; 3. Have made regular use of medication in the last 4 weeks prior to the start of the study or have made use of any medication a week before the study began; 4. Have been hospitalized for any reason, up to 8 weeks before the study; 5. Provide history of alcohol abuse, drugs or medications, or have ingested alcohol within 48 hours prior to the period of hospitalization; 6. Have a history of liver disease, renal, pulmonary, gastrointestinal, hematological or psychiatric; 7. Amendments pressure of any etiology requiring pharmacological treatment; 8. Present history of myocardial infarction, angina and / or heart failure.