A Study of MK2206 in Locally Advanced or Metastatic Solid Tumors (2206-007)

Inclusion Criteria: * Patient must have confirmed locally advanced or metastatic solid tumors that have failed to respond to standard therapy, have gotten worse or have come back after existing therapy * Has adequate organ function * Is ECOG Performance Scale 0-1 * Has a negative urine pregnancy test if patient is female * Is able to swallow capsules and has no surgical or bodily condition that will prevent the patient from swallowing and absorbing oral medications on an ongoing basis Exclusion Criteria: * Patient has had chemotherapy, radiotherapy, biological therapy or surgery within 4 weeks of starting the study and has not recovered from adverse events caused by the treatment * Is currently participating or has participated in a study with an investigational compound or device within 28 days * Has a primary central nervous system tumor * Has a history or current evidence of heart disease, slow heart rate or untreated high blood pressure * Is a known diabetic who is taking insulin or oral antidiabetic therapy * Is pregnant or breastfeeding or planning to become pregnant during the study * Is positive HIV antibody, HBs antigen or HCV antibody