For some years, the investigators observe an increase of the arisen of diabetes in cystic fibrosis patients However, this diabetes may be reversible. The investigators speak about " Cystic fibrosis related diabetes.". The objective of this project, is to know better what facilitates the appearance and the reversibility of the diabetes, such as the genetic mutations, the respiratory state and the lung infections. Theses knowledges should allow to adapt the screening of diabetes, and its treatment, for the patients affected by cystic fibrosis.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
OTHER
Masking
NONE
Enrollment
230
Annualfollow-up including : * oral glucose tolerance test * dietary survey * biological evaluation * bacteriological and respiratory measures * dual-energy x-ray absorptiometry * physical activity survey
Service de Médecine Interne - Centre Hospitalier Lyon Sud
Pierre-Bénite, France
Describe the natural history of the glucose tolerance in cystic fibrosis patients and to identify the predictive factors of the reversibility or the aggravation in the disorders of the glucidic metabolism.
Time frame: 3 years
Estimate prevalence of the various stages of disorders of the glucose metabolism : glucose intolerance and diabetes
Time frame: 3 years
Estimate the probability of arisen the complications associated to the disorders of the glucidic metabolism : - deterioration of the respiratory function, - lung exacerbations - alteration of the nutritional state
Time frame: 3 years
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