Efficacy and Safety Study of Polidocanol Injectable Foam for the Treatment of Saphenofemoral Junction (SFJ) Incompetence

Inclusion Criteria: * Incompetence of SFJ associated with incompetence of the GSV or other major accessory vein * Ability to comprehend and sign an informed consent document and complete study questionnaires in English * Ability to record symptoms in accordance with the protocol * Symptomatic varicose veins * Visible varicose veins Exclusion Criteria: * Patients who only have telangiectatic or reticular veins (Clinical Finding C1, as assessed by CEAP (clinical, etiologic, anatomic, and pathophysiologic) Classification of Venous Disorders). * Leg obesity impairing the ability to access the vein to be treated and/or to apply postprocedure compression bandaging and stockings * Ultrasonographic or other evidence of current or previous deep vein thrombosis or occlusion * Deep vein reflux unless clinically insignificant in comparison to superficial reflux * Peripheral arterial disease precluding the wearing of post-procedure compression bandaging and stockings * Reduced mobility * Major surgery, prolonged hospitalization or pregnancy within 3 months of screening * Major co-existing disease (e.g. malignancy; pulmonary disease; renal or hepatic insufficiency; serious skin disease/condition that may compromise the ability of the patient to comply with the compression protocol, etc.) * Known allergic response to polidocanol or heparin, including history of heparin-induced thrombocytopenia, and/or multiple allergic reactions * Current alcohol or drug abuse * Pregnant or lactating women * Women of childbearing potential not using effective contraception * History of DVT, pulmonary embolism or stroke