Assessment of Stent Strut Coverage and Endothelial Function After Drug-Eluting Stents

Inclusion Criteria: * Significant coronary de novo lesion (\> 70% by quantitative angiographic analysis) * Patients with stable or acute coronary syndrome considered for coronary revascularization * Reference vessel diameter of 2.5 to 3.5 mm by operator assessment Exclusion Criteria: * Contraindication to anti-platelet agents * Ostial lesion within 5 mm from ostium * Different DES in other vessel simultaneously * Creatinine level 2.5 mg/dL * Left main stenosis more than 50%. * vein graft lesion * Triple vessel disease with stenosis more than 50% in 3 epicardial coronary arteries * Life expectancy 1 year * Reference vessel \< 2.5 mm or \> 4.0 mm diameter by visual * Long lesion that require more than three stents