A single dose, two treatments (two cephalexin suspension brands), two sequences, cross-over design was used with a washout of 7 days between the two study periods. Treatment groups balanced with the same number of healthy volunteers who were randomly (in two strata: male and female) assigned to the study drug administration sequences.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
26
Single dose of 500 mg / 10 mL
Single dose of 500 mg / 20 mL
Unnamed facility
Morelia, Michoacán, Mexico
Least square estimator of average maximum plasmatic concentration (log transformed)
Time frame: After two months
Least square estimator of area under the pharmacokinetic curve (log transformed)
Time frame: After two months
Time at which maximum concentration is reached
Time frame: After two months
Area under the pharmacokinetic curve from time=0 to last blood sample
Time frame: After two months
Clearance constant of plasmatic concentration of study drug
Time frame: After two months
Half life of plasmatic concentration of study drug
Time frame: After two months
Adverse events collection
Time frame: Up to 6 weeks
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.