Primary purpose : to assess the effect on neuropsychological tasks related to planning of 10 daily sessions of right dorsolateral prefrontal cortex with High-frequency repetitive transcranial magnetic stimulation (rTMS) on borderline personality disorder (BPD) patients. Hypothesis : BPD patients receiving 10 sessions of rTMS will have greater improvement in the average number of move to achieve tasks of the Tower of London, than those receiving sham rTMS.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
13
The motor threshold was determined in each subject once, before treatment. This was defined as the lowest stimulation intensity capable of inducing a visible movement at least five times out of 10 stimulations. The position of the right dorsolateral prefrontal cortex was defined as 5 cm anterior (in a parasagittal line) to the motor cortex. The stimulus intensity was 80% of the patient's motor threshold intensity. Treatments were given for 20 minutes per day over 10 working days.
sham rTMS
Lionel Cailhol
Toulouse, University Hospital Toulouse, France
Tower of London
Time frame: Inclusion, 15th day, 30th day and 3rd month
Balloon Analog Risk Task
Time frame: Inclusion, 15th day, 30th day and 3rd month
Micro-World Test
Time frame: Inclusion, 15th day and 3rd month
Borderline Personality Disorder Severity Index
Time frame: Pre-inclusion, 30th day and 3rd month
Symptom Check List - 90
Time frame: Inclusion, 15th day, 30th day and 3rd month
Barratt Impulsivity Scale
Time frame: Inclusion and 3rd month
Global Assessment Scale
Time frame: Inclusion and 3rd month
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