Evaluation of Microbial Colonisation and Contamination Caused by the Transvaginal and Transabdominal Access for Cholecystectomy

Cantonal Hospital of St. Gallen30 enrolled

Overview

Transvaginal hybrid procedures are of interest as an available NOTES procedure for the clinical routine. The gynaecologists' experiences and the available studies report on low morbidity related to the transvaginal access. However, little is known about the vaginal and intraabdominal microbial contamination due to the transvaginal approach. The aim of this cohort study is to evaluate the microbial colonisation and contamination in patients with transvaginal hybrid and conventional laparoscopic cholecystectomy. Therefore, pre- and intraoperative microbiological evaluations will be performed in patients with transvaginal hybrid cholecystectomy and laparoscopic cholecystectomy.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Cholecystectomy

Interventions

Smear test vaginally, intraabdominallyPROCEDURE

Pre- and intraoperative smear tests of the vagina and douglas are performed.

Eligibility

Sex: FEMALEMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * indication for elective cholecystectomy * informed consent for laparoscopic cholecystectomy or transvaginal hybrid cholecystectomy Exclusion Criteria: * cholecystitis * intraabdominal infection * existing antibiotic therapy * adnexitis * pelvic inflammatory disease * infection (CRP \> 10 mg /l; Lc \> 11 G/l)

Outcomes

Primary Outcomes

Microbial colonisation and contamination vaginally and intraabdominally

Time frame: 1 day

Secondary Outcomes

Morbidity (wound, vaginal and intraabdominal infection) two weeks and six weeks postoperatively

Time frame: 6 weeks