Plasmapheresis for Nephrogenic Fibrosing Dermopathy (NFD)/Nephrogenic Systemic Fibrosis (NSF)

Phase 4TerminatedNCT01078987

Loma Linda University12 enrolled

Overview

The purpose of this study is to evaluate the pathophysiology of nephrogenic fibrosing dermopathy (NFD)/nephrogenic systemic fibrosis (NSF).

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Nephrogenic Fibrosing Dermopathy Nephrogenic Systemic Fibrosis

Interventions

PlasmapheresisPROCEDURE

A course of 5 daily treatments of plasma exchange (plasmapheresis) for one to three courses

Eligibility

Sex: ALLMin age: 18 YearsMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * diagnosed with NFD/NSF following a kidney transplant * diagnosed with NFD/NSF following a liver transplant * NFD/NSF and who have not had a kidney or liver transplant * diagnosed with NFD/NSF and who have not had a kidney or liver transplant

Locations (1)

Loma Linda University Medical Center

Loma Linda, California, United States

Outcomes

Primary Outcomes

Improve elasticity of skin, including increased range of motion of compromised joints due to leathery skin

Time frame: Assessed two weeks after each monthly course of plasmapheresis

Data from ClinicalTrials.gov

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