Effect of Intermittent Pneumatic Compression on Ulcer Healing in Subjects With Secondary Lymphedema

Inclusion Criteria: * Diagnosed with secondary lymphedema * Presence of a venous ulcer that has not healed in more than 6 months * Localized wound pain greater than 3 with VAS * Ulcer must be on lower leg (below knee) * Ulcer must be of venous etiology * CVI proven by duplex studies * Subject must have adequate arterial blood flow (ABI \> 0.70) * Subject must be able to tolerate compression bandages * Subject must be ambulatory * Capable of understanding consent process Exclusion Criteria: * Wound infection * Ulcer of non-venous etiology * Ulcer on toes or plantar surface of the foot * Subject taking any medication that in the opinion of the investigator affects wound healing * Alcohol or drug abuse * Active deep venous thrombosis (DVT) * Subject has a cancer diagnosis * Diabetic with hemoglobin A1C\>12 * Arterial insufficiency ABI\<0.70 * Subject is not capable of walking (wheelchair-bound or bed-bound) * Subject currently enrolled in another clinical trial * Moderate to severe congestive heart failure