Cardiac Magnetic Resonance in Children With Muscular Dystrophy

Cooperative International Neuromuscular Research Group20 enrolled

Overview

This protocol will exploit novel state of the art cardiovascular magnetic resonance techniques to examine important changes in the heart in children with muscular dystrophy. The purpose of this study is to compare cardiac magnetic resonance (CMR) with the collected cardiac outcome data obtained in protocol: PITT1109 - Cardiac Outcome Measures in Children with Muscular Dystrophy.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Duchenne Muscular Dystrophy Becker Muscular Dystrophy Limb Girdle Muscular Dystrophy

Eligibility

Sex: ALLMin age: 8 YearsMax age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Participant enrolled in the CINRG study: PITT1109 - Cardiac Outcome Measures in Children with Muscular Dystrophy Exclusion Criteria: * Pregnant woman (when uncertain, participants will undergo urine testing) or lactating women * Decompensated congestive heart failure (unable to lie flat during CMR) * Impaired renal excretory function (calculated Glomerular Filtration Rate less than 30mL/min) * Contra-indications to Magnetic Resonance Imaging: * Cardiac pacemaker or implantable defibrillator * Cerebral aneurysm clip * Neural stimulator * Metallic ocular foreign body * Harrington-rod * Any implanted device (i.e. insulin pump, drug infusion device) * Claustrophobia * Metal shrapnel or bullet

Locations (2)

Children's National Medical Center

Washington D.C., District of Columbia, United States

University of Pittsburgh

Pittsburgh, Pennsylvania, United States

Data from ClinicalTrials.gov

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