To compare heart function, symptoms, exercise capacity and quality of life in patients with Congestive Heart Failure (CHF) and Atrial Fibrillation (AF)before and after catheter ablation. Hypothesis: Restoration and maintenance of sinus rhythm by catheter ablation, without the use of antiarrhythmic drugs, in AF and CHF improves heart failure status.
Study Type
OBSERVATIONAL
Subjects with clinical indication for PVI, either paroxysmal or persistent AF failing medical management with rate or rhythm control medications.
The Valley Hospital
Ridgewood, New Jersey, United States
St.Luke's-Roosevelt Hospital
New York, New York, United States
Improvement in LVESV by 15% or more from baseline at 6 months
Time frame: 6 months
Remodeling as demonstrated by atrial & ventricular dimensions on echocardiogram
Time frame: 6 months
NYHA Class
Time frame: 6 months
Quality of Life
Time frame: 6 months
Six minute hall walk test
Time frame: 6 months
Hospitalization for HF
Composite hospitalization for HF,thromboembolic complications, major bleeding or all cause mortality
Time frame: one year
Absence of Atrial fibrillation
Time frame: one year
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